Supercomputer creates the most realistic virtual brain ever

Researchers have created one of the most detailed virtual mouse cortex simulations ever achieved by combining massive biological datasets with the extraordinary power of Japan’s Fugaku supercomputer. The digital brain behaves like a living system, complete with millions of neurons and tens of billions of synapses, giving scientists the ability to watch diseases like Alzheimer’s or epilepsy unfold step by step. The project opens a new path for studying brain function, tracking how damage spreads across neural circuits, and testing ideas that once required countless experiments on real tissue.

Scientists uncover meditation’s hidden side effects

Meditation is widely praised for its mental health benefits, but new research shows that it can also produce unexpected side effects for some people—from anxiety and dissociation to functional impairment. Psychologist Nicholas Van Dam and his team found that nearly 60% of meditators experienced some kind of effect, and about a third found them distressing.

Resetting the body’s rhythm could protect the brain from Alzheimer’s

Researchers discovered that altering the body’s natural rhythm can help protect the brain from Alzheimer’s damage. By turning off a circadian protein in mice, they raised NAD+ levels and reduced harmful tau buildup. The findings suggest that adjusting the body’s clock may one day help prevent neurodegeneration.